With this project, Marja Jäättelä and her group will map how different types of dietary fats are used as building blocks in cells and how they affect their functions. The ultimate aim of the project is to enable a better use of diets in the prevention and treatment of various diseases.
Marja Jäättelä says: “We know today that there are different types of fats in our food and that they have both good and harmful effects on our health. But we do not know so much about how these fats distribute in our body or how they affect different tissues. Therefore, we wish to investigate how different types of fats in food are used in the body. For this purpose, we will feed mice with excess of specific dietary fatty acids and then determine the fat composition of cellular membranes and other lipid-containing molecules in various tissues.”