Microorganisms such as yeast can produce natural chemicals from other other organisms such as plants in a sustainable manner. This involves genetically engineering the yeast to produce the right plant enzymes but does not always work. Microorganisms have different internal environment than plants which may interfere with the enzymes. Here, we engineer a new compartment in the microorganism – a membrane-less organelle. The membrane-less organelles should act as a reaction chamber than isolate the new enzymes from the life processes of the host and vice versa. This organelles should concentrate the right enzymes and their substrates and exclude interfering enzymes. We hypothesize that such structures will accelerate the reaction and reduce formation of by-products and can be used to produce many different chemicals. We will focus on enzymes producing natural colourants as a test case to explore general principles governing enzyme containing membrane-less organelles.