Johan Burisch says: “Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis, are chronic diseases caused by abnormal inflammation in the intestinal tract. Patients are often diagnosed in early adulthood and face a lifetime of suffering from a disease that currently has no cure. It is of major importance to identify patients at an early stage who later develop aggressive disease to offer these patients close follow-up and individually tailored medication. Currently, we do not understand why some patients experience a mild disease course and others suffer from aggressive disease. In this project, we will combine clinical, genetic, gut microbiome and serological information to be able to predict – at diagnosis – which disease path a newly diagnosed young patient will take and thereby enable physicians to choose the right treatment for the right patient and improve their disease course.”