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Grant recipient

Christian Kanstrup Holm

Exploring metabolic pathways to fight Pandemic viruses
Grant amount: DKK 9,978,838
Christian Kanstrup Holm says: “Anti-viral therapies for infection with Corona Viruses and most other human pathogenic viruses do not currently exist. The prevention of pandemics, such as the current SARS-CoV2 pandemic, thus relies on vaccines that can only be developed months to years after the pandemic has spread. For these reasons, the human population is very vulnerable to new pathogenic viruses. The identification of cellular pathways that could be targeted with new anti-viral therapies is thus highly desirable. Immunometabolism is a new field of research with promising potential. Research within this new field has revealed that basal metabolic pathways are important for control of viral replication. With this new and ambitious proposal, we will identify metabolites and metabolic pathways that can be exploited for the development of novel broad-spectrum anti-viral therapies that target SARS-CoV2 (causative agent of COVID-19) and influenza A virus. These two viruses both have severe impact of World health.”
Christian Kanstrup Holm
Christian Kanstrup Holm
Associate Professor, Department of Biomedicine, Aarhus University