Grant recipient

Anne Hammer Lauridsen

Unravelling the molecular mechanisms in viral transformation and progression of HPV-related disease
Grant amount: DKK 9,994,209

Anne Hammer Lauridsen says: “Globally, 8.6% of all female cancers can be attributed to human papillomavirus (HPV). The purpose of this project is to explore the underlying mechanisms for why HPV causes the development of cancer in some women, but not in all those infected with the virus. A better understanding of the molecular mechanisms in the development of HPV-related disease of the cervix may enable an identification of novel biomarkers applicable to screening, clinical management, and treatment, thereby potentially reducing risk of under- and overtreatment. In the proposed project, we will use tissue samples from women with premalignant cervical lesions and women with cervical cancer. To explore the molecular mechanisms, we will perform state-of-the-art molecular analyses, including mutation analysis and an analysis of the women’s immune response to the virus. Results from the proposed project will be important not only for our understanding of HPV-related cervical disease, but also for other HPV-related diseases.”

Anne Hammer Lauridsen is Senior Consultant and Head of Research at Department of Obstetrics and Gynecology, Gødstrup Hospital. Anne Hammer Lauridsen has been Clinical Associate Professor at Department of Clinical Medicine, Aarhus University, since 2022.

Anne Hammer Lauridsen
Senior Consultant
Dept. of Obstetrics and Gynecology, Gødstrup Hospital