menu

Rasmus Pagh

How do we ensure that we can trust systems that use data to make decisions? Lawmakers across the world are grappling with the question of how to properly regulate systems that collect, analyze, and use data. Getting the balance right is crucial. Too little regulation could increase the risk of compromising basic societal values and privacy. Too strict regulations will limit our possibilities for realizing the value and societal benefit of AI and big data analytics.

The Providentia project will advance algorithms for integrating and analyzing sensitive data – such as health data or medical records – in a secure way that preserves privacy and does not require all data to be transferred to a central location.

During the last decade, differential privacy has emerged as the gold standard for protecting private information, based on firm mathematical guarantees on how much private information can be deduced from data sets, analyses, or predictions that are released. Extending recent developments, the project will establish a research group focusing on differentially private algorithms in distributed settings. The goal is to enable data science when no entity holds all relevant data, and where privacy considerations make it impossible or undesirable to consolidate all data for central analysis. This is relevant, for instance, when using healthcare data to improve health outcomes via better prevention, diagnosis and treatment of disease.

The project name is inspired by the ancient Roman goddess Providentia who personifies the ability to foresee events and make suitable provision. In this spirit, the Providentia project seeks to provide the forethought needed to ensure that data scientists can make use of valuable sources of insight, also when data contains sensitive information.

Charlotte Ling

Moustapha Kassem

Inge Marie Svane

Trine Mogensen

Robert Fenton

Anja Groth

Anja Groth says: “Epigenetic cell memory guides embryonic development and counteract disease in adults. All cells in our body contain the same DNA sequence, yet cells have distinct properties matching their functions as for example nerve or muscle cells. During development, this complexity arises gradually through activation and maintenance of different gene regulatory programs. The genome is organized into a structure called chromatin, which sets the stage for gene regulation and allows the proper programs to be executed while setting a barrier for expression of unwarranted genes. Chromatin structure can be propagated to daughter cells, providing epigenetic cellular memory that maintains cell identity and fate. Histone proteins, the core component of chromatin, can be chemically modified and these modifications are thought carry epigenetic information. This research project will dissect molecularly how histones are inherited to daughter cells and reveal their function in epigenetic cell memory.”

Niels Richard Hansen

Susanne Ditlevsen

Claus Højbjerg Gravholt