Stefanie Rosa
Water is essential for life, but some organisms can survive extreme dehydration, a phenomenon called anhydrobiosis. Orthodox plant seeds are remarkable examples, capable of enduring desiccation and surviving harsh conditions for years, even millennia. This ability allows seeds to remain dormant until favorable conditions arise. However, desiccation poses challenges, including oxidative stress and molecular damage, particularly to DNA. Damaged DNA can prevent germination and hinder development after rehydration, yet the mechanisms protecting DNA during these processes remain largely unknown. In this project, I aim to uncover the mechanisms that safeguard genome integrity in desiccated seeds and enable successful germination. By addressing this knowledge gap, we hope to improve seed vigor, longevity, and resilience in crops, contributing to agricultural productivity and global food security.