Grant recipient

Trisha Grevengoed

Fat forward in the fight against heart disease: novel omega-3 lipid metabolites to lower triglycerides and cardiovascular disease risk
Grant amount: DKK 10,000,000

Trisha Grevengoed says: “Cardiovascular disease is the leading cause of death worldwide, so reducing its incidence is imperative. Omega-3 fatty acids are often given as a treatment to lower blood triglycerides to help prevent cardiovascular disease events, such as heart attack or stroke. Despite their wide use, we do not fully understand how omega-3 fatty acids work. I will examine a novel role for omega-3 fatty acids and their products in relieving heart disease and its causes. I propose that previously unstudied molecules made from omega-3 fatty acids can directly lower blood triglycerides and inflammation and limit progression of heart disease. I will test this hypothesis by developing new models with altered amounts of these molecules in order to study their importance in human health. When completed, I hope this work will be able to help alleviate heart disease and diminish its comorbidities to improve the quality of life for many people.”

Trisha Grevengoed is American and currently at the Novo Nordisk Foundation Center for Basic Metabolic Research. With the Hallas-Møller Emerging Investigator grant she will establish her own research group as assistant professor at the Department of Biomedical Sciences where the departmental focus on cardiac health and Trisha’s focus on lipids and metabolism is mutually beneficial for the project.

Trisha Grevengoed
Trisha Grevengoed
Group Leader, Department of Biomedical Sciences, University of Copenhagen