Grant recipient

Nicolai Wewer Albrechtsen

The Postprandial Human Liver
Grant amount: DKK 9,767,500

In this project Nicolai Albrechtsen aim to understand how the human liver ‘works’ when we eat and which biochemical systems within the liver that are impaired in obese individuals and patients with liver diseases. By bridging an advanced clinical setup in humans to state-of-the-art biochemical techniques such as mass-spectrometry and machine learning the goal is to provide the first ‘postprandial human liver atlas’. Evaluating liver profiles of healthy compared to those with liver disease may guide us to a new understanding of how the human liver works and thereby also aid in the identification of new drug targets for liver diseases.

Nicolai Albrechtsen says: “Overload of nutrients and sedentary life predisposes to obesity and liver diseases. Every time we eat, thousands of biochemical processes are activated in order to help our body digest carbohydrates, proteins and fat. The liver is of particular importance for such as it filters and regulates the amount and type of nutrients that reaches our organs”.

Nicolai Wewer Albrechtsen
Senior Resident, Department of Clinical Biochemistry and Department of Biomedical Sciences
Rigshospitalet and University of Copenhagen