Grant recipient

Merete Nordentoft

The Danish High Risk and Resilience Study – VIA 15. A Longitudinal Study of Children Born to Parents with Schizophrenia, Bipolar Disorder and Controls
Grant amount: DKK 10,000,000
Merete Nordentoft says: “The Danish High Risk and Resilience study – VIA 7 was established in 2013–2015 as a representative cohort of 522 7-year old children with parents with schizophrenia or bipolar disorder and control parents. Symptoms, neurocognition, motor function, language and general well-being were thoroughly assessed at age 7 years and again at age 11 years in the VIA 11 study. Magnetic resonance brain scanning was conducted in VIA 11. In VIA 7, we found that especially children of parents with schizophrenia had more symptoms, poorer social, neurocognitive and motor functioning compared with children in control families. With the Danish High Risk and Resilience Study VIA 15, we can investigate whether these poor outcomes are worsened, unchanged or improved. Magnetic resonance scans in VIA 11 and VIA 15 will for the first time make it possible to study structural and functional brain changes during disease formation. We will get better insight into aetiology, disease formation and disease trajectories, and we will be able to identify possibilities for early intervention.”
Merete Nordentoft
Merete Nordentoft, professor
Region Hovedstadens Psykiatri