Grant recipient
Industrial biotechnology relies on specific microorganisms to perform specialized tasks. Just as conventional brewing relies on the efficiency of yeast to ferment, a green economy aiming at mitigating atmospheric CO2 requires the best possible organism for CO2 valorization. In this project, I aim to use evolution as a tool to help identify this new “yeast” for CO2 valorization. Once this organism is identified, I will focus on its thorough characterization by creating a collection of genetic mutants and analyzing them using automated robotic systems. I will also assess the potential of this strain as a platform for bioproduction by manipulating its metabolism to enhance its ability to “eat” CO2 and convert it into valuable molecules for societal use. If successful, this project will provide the scientific community with a new "yeast for CO2 valorization", establishing a reference organism for future efforts aimed at CO2 bioconversion.
Enrico Orsi
Universal methylotrophic unlocking through evolution and engineering for sustainable one-carbon biomanufacturing (UNMUTE)
Grant amount: DKK 11.250.000